High Court Judge Redson Kapindu said after careful scrutiny of evidence brought in the court by the prosecution team, he found the five with no case to answer.
However, Kapindu has ruled that the remaining six other suspects have a case to answer, and the matter has since been adjourned to June 24 this year.
In February this year, the court convicted two people, Kenneth Moses and Herbert Maloni after they pleaded guilty to murder charge.
The duo’s sentencing is pending conclusion of the trial of the remaining accused persons who pleaded not guilty.
State Prosecutor Dziko ndi anthu Malunda said they were satisfied with the ruling and were looking forwad to the judgement.
"A number of accused persons have been acquitted and the remaining accused have been found with a case to answer. For us, that is okay because it means that the Judge has assessed all the evidence and has come up to a decision which we are satisfied with," Malunda said.
Over 24 persons with albinism have been killed in Malawi in the past two years, with suspects believing that their body parts can make them rich.
President Professor Arthur Peter Mutharika has instituted several measures to stop the vice, including rolling out a national plan of action to protect the 10,000 strong population.